KinemaScan is the newest addition to our NeurodegenScan Suite and provides a multi‐dimensional ventral and side‐view kinematic gait analysis of animals. Kinematic Gait analysis allows highly sensitive, noninvasive detection and evaluation of many pathophysiological conditions, such as those occurring in Spinal Cord Injury, Parkinson’s disease, Alzheimer’s disease, ALS, arthritis, pain, neuromuscular and skeletal muscle diseases.
KinemaScan is a multi‐dimensional analysis system that takes video of animal (mouse/rat/guinea pig) running on a transparent belt treadmill as input from 2 different views: Ventral view for traditional TreadScan based video analysis and Side view for joint‐motion Kinematic Analysis. The ventral and side‐view videos of the animal are obtained using a pair of high‐speed digital cameras and each video capture can be 20 seconds (or even more when used with specialized fast hard drive architecture) giving a multitude of stride samples in just one trial. The ventral view video essentially captures the foot prints of the animal as they walk/run on the treadmill. The side view video captures motion of the joints using reflectors or color markers affixed to the landmark points on the animals’ limbs. Both views are synchronized during video capture.
KinemaScan can reliably analyze these multi‐dimensional synchronized video, and determine various characteristic parameters that are related to the pathophysiological conditions. These parameters include all traditional ventral view gait parameters provided by TreadScan including stance time, swing time, total stride time, stride length, foot contact area size, foot pressure (measured using color intensity levels), body‐foot spacing distance (distances between body and feet), foot spacing distances (distance between various feet), running speed, stride frequencies, foot coupling or coordination measures (in‐phase or out‐of‐phase gait patterns of feet), and Foot Print Analysis related measures such as foot print placement rotation angle with body and toe spread factors (splay) among many others. However, KinemaScan also provides Side View kinematic Joint movement data using markers placed on joints that includes Joint Trajectories or Tracks over time and their patterns, Joint angles between surrounding joints and there variation over time among many others.
KinemaScan outputs the detailed results of these parameters from analysis into Microsoft Excel files and gives statistical results to meet requirements in the research. Advanced functionalities such as batch mode analysis, group export, direct analysis of AVI captured files, and post‐hoc conversion to compressed MPEG videos to save disk‐space are available. A sample screenshot of the TreadScan software is shown below. The stride data is shown on the right for each foot individually. The results are updated as the analysis takes place.
•Complete GLP‐compliant System
•Analyzes video at speeds of up to 175 fps and video resolution up to 656×480 in each view
•Detects feet in animals with almost similar coat color like Agouti and White mice!
• Works with rodents of all colors/sizes
• Stores video in MPEG with high‐compression for optimal use of disk space
• Provides a Comprehensive set of gait measures
• Export Stance Graph (a timing diagram of the foot stances and the foot contact size information) and the Ink‐Pad image showing the foot placement positions
• Ability to automatically flag outliers for further review and discard unusable portions of video